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A global partnership to accelerate the fight against HIV/AIDS
CREATING A FAST LANE FOR CHANGE
New interventions and technologies to change the face of HIV/AIDS




                                             “The future belongs to people who see
                                              possibilities before they become obvious.”
                                             — Ted Levitt, American Economist


                                             There are great ideas — simple, innovative, high-impact — emerging in
                                             the fight to prevent and treat HIV/AIDS. But a dearth of funds means some
                                             of the best never have the chance to come to life.

                                             The UNICEF HIV/AIDS Innovation Fund seeks to harness the greatest
                                             minds, most effective technologies, and best approaches to ensure
                                             even the hardest-to-reach children and families can lead healthy lives
                                             free of HIV.

                                             We invite you to join us in the next phase of the fight against HIV/AIDS.
THE NEED FOR A NEW WAY FORWARD
Working together toward an HIV-free generation




   34 million people  2.5 million children — including                              — are living

                 400,000 children 900,000
   with HIV/AIDS today. More than                                   and

   adolescents become newly infected each year. Vast segments of affected populations —
   especially women and children — are not being reached by current approaches to

   prevention and treatment. At the same time, the funding gap between what is needed to respond

   to the global HIV/AIDS epidemic and what is available continues to grow, reaching $10 billion

   in 2010. There is an urgent need for a re-energized response to HIV/AIDS — to bring low-cost,

   high-impact interventions and technologies to scale. And we need your help.
MOVING TOWARDS AN HIV FREE GENERATION
1.26 million children and young people are newly infected by HIV each year.
By 2015 we aim to reduce this number by 50%.



    To do this UNICEF and partners will:

     Reduce new infant infection by 90%                        Reduce new youth infection by 30%




    From 370,000 to 37,000


                                                              From 890,000 to 623,000

    Each figure represents 10,000 children newly infected each year.
A FUND TO BRING INNOVATION TO SCALE
The UNICEF HIV/AIDS Innovation Fund brings together top HIV experts with diverse business
and philanthropic leaders to invest in high-impact, low-cost interventions and technologies that
can change the face of the AIDS epidemic.

How it works:

  UNICEF sources the most                                 The Fund incubates          UNICEF works with governments,
  innovative ideas                                        these ideas,                NGOs, academia, and multilateral
  — with the power to address                             providing financing         partners to bring the most
  unmet needs and hard-to-reach                                                       successful projects to


                                                                                  3
                                                          and expertise through
  populations — from experts                              the pilot phase.            scale, breaking bottlenecks,

                              1
  and partners working in                                                             boosting capacity, and encourag-
  more than 150 countries.                                                            ing new commitments.
                                                                                                            4
                                  The Fund’s Advisory                                 Funders and partners receive
                                  Committee recommends                                narrative and financial reports
                                  the highest-                                        helping them monitor
                                  potential                                           investments and continually
                                  projects                                            align funding with the
                                                                                      most effective
                                                      2
                                  for seed funding.
                                                                                      innovations.
                                                                                                                  5
KEY ELEMENTS OF THE INNOVATION FUND
Rapid, flexible resources building a pathway to scale




   •	 Pooled   fund of $4-5 million/year.

   •	 Transparent criteria and process for selection of projects, including defined   metrics for
      measuring success/impact.

   •	 Provision of rapid, flexible resources during the early stages of a project’s life cycle, building
      a pathway to scale up by governments and donors.

   •	 Advisory Committee comprised of HIV experts and lead              funders working together
      to recommend the highest-potential projects for seed funding.

   •	 External/private sector expertise leveraged to strengthen     projects as needed.

   •	 Five year initial   phase from 2011 to 2015, with annual review of results and impact.
INNOVATION FUND TARGET AREAS FOR INVESTMENT
Investing for impact



   Solutions for “Last Mile” Delivery
      •	   Strengthen drug and local supply chains
      •	   Ensure drug delivery and uptake by hardest-to-reach populations
      •	   Facilitate improved disease reporting, test result delivery and treatment monitoring
      •	   Develop open-source mobile technology for integrated health services

   Innovation in the Youth Agenda
      •	 Reimagine youth-friendly HIV/AIDS prevention and treatment platforms
      •	 Empower youth through technology, social networks, and other new media
      •	 Enable peer-to-peer communication and support

   Strengthening Families and Communities
      •	 Build social and economic systems that incentivize well-being and facilitate access to health care for the hardest-to-reach
      •	 Design resources for community-based healthcare and education.

   Optimizing Management Systems
      •	 Maximize cost effectiveness of interventions and outcomes
      •	 Improve data use and management
INNOVATION FUND PROJECT SELECTION CRITERIA
Breaking bottlenecks, delivering results, positioning for scale



 •	 Focus on new interventions and technologies, or innovations to current approaches
    that contribute to reducing the impact of HIV/AIDS on women and children.

 •	 IIdentify specific          bottlenecks to be addressed and show how the project can help change
    the HIV/AIDS landscape.

 •	 Be evidence-based and contribute on-the-ground                   results within 2–3 years.

 •	 Demonstrate how “proof-of-concept” could lead to scale-up              and funding
    by governments and donors.

 •	 lBuild     on partnerships on the ground, link with national oversight.

 •	 Use existing global and national data and indicators to measure   projects’ success.

 •	 lBe   fundable with approximately $500K per project.
INNOVATION: Results160 MOBILE HEALTH                                                                                                                                                                        Example

RapidSMS improves access to HIV test results and services for women and infants



 Bottleneck
 Transportation barriers and logistical delays lead to slow reporting
                                                                                                                                                                                         If positive, child starts treatment
 of HIV test results, delaying Early Infant Diagnosis and inhibiting                                                                                                             13
                                                                                                                                                                                         If negative, child retested in 6 mos.

 treatment for mothers and infants.                                         All pregnant mothers tested
                                                                                                                                        Mother retrieves DBS results from clinic,
                                                                        1
                                                                        0
                                                                                                                                        & results are logged in child’s Under 5 Card
                                                                                                                                12

 Solution
                                                                            Baby born to HIV+ mother
                                                                        1
                                                                                                                       Mother is
                                                                                                                                                                  SMS
 RapidSMS mobile phone technology increases the number of                                                      11
                                                                                                                       contacted                                 System


 infants accurately tested for HIV and drastically reduces parents’                                                                                                                                 Results processed and
                                                                                                                                                                                                    sent to clinic via SMS
                                                                                                                                                                                                9
 wait time for results.                                                                                                                             Results received by
                                                                                                                                                    clinic worker & logged
                                                                                                                                               10                                                                  LAB
                                                                                                                                                                                                                   Lab receives

 Result                                                                            CLINIC                                                               HUB CLINIC
                                                                                                                                                                                     2                         8
                                                                                                                                                                                                                   samples
                                                                                                                                                                                 2
                                                                                                                   2
 Low cost text messaging leads to 50% improvement in the
                                                                                                                                                                                                                     DBS Sample
                                                                                                                                                                                                                      DBS Sample


                                                                                                               2
                                                                                                                                                                                                                        DBS Sample
                                                                                                                                                                                                                          DBS Sample
                                                                                                                                                                                                                            DBS Sample


                                                                                                                                                                           Hub Clinic receives
                                                                                                                                                                           & logs samples
 delivery of HIV results for infants and helps ensure treatment                 DBS sample taken at
                                                                                                                                                                  6
                                                                                rural clinic
 availability and adherence.                                                2                                                                                    DBS Sample
                                                                                                                                                                  DBS Sample
                                                                                                                                                                    DBS Sample
                                                                                                                                                                                 DBS Sample
                                                                                                                                                                                           1
                                                                                                                                                                                  DBS Sample




                                                                                                                                                                                                     7 Hub aggregates samples

 Benefits                                                                                                              3
                                                                                                                           Samples packed
                                                                                                                           & logged
                                                                                                                            1
                                                                                                                                                          5 Samples transported
                                                                                                                                                                                                         and sends to Lab
                                                                                                                                                                                                                                 7

     •	   Speed — Wait time for test results cut from months to days.                 Dried Blood Spot (DBS)
                                                                                                                                                              to district Hub Clinic


     •	   Cost — No SMS cost for clinic staff.
                                                                                             Sample
                                                                                                                               DBS Sample
                                                                                                                                DBS Sample
                                                                                                                                  DBS Sample
                                                                                                                                                    4 SMS
                                                                                                                                                        “SENT #” samples
     •	   Scale — Potential for national scale at low cost.
     •	   Reporting — Web portal provides national view of HIV
          rates and treatment.
OPPORTUNITIES TO HELP DRIVE THE HIV/AIDS INNOVATION FUND
UNICEF and Business and Philanthropic leaders changing the face of HIV/AIDS




                                             UNICEF as a Partner for Innovation
                                             UNICEF has offices in more than 150 countries worldwide, and a long history of identifying
                                             and scaling innovative solutions to development challenges. We are looking for partners
                                             who share our belief that the next step in the fight against HIV/AIDS calls for new col-
                                             laboration models and a willingness to embrace innovation.


                                             Become a Seed Funder
                                             Make a substantial, multi-year contribution to help seed the Fund and you’ll join the
                                             Fund’s Advisory Committee — a multi-disciplinary group of corporate and philanthropic
                                             leaders, and top HIV experts.

                                             Leverage Your Network
                                             If you know investors for whom the Innovation Fund would be of interest, please
                                             put them in touch with the U.S. Fund for UNICEF.
CONTACT US
For more information, please contact:




                                        Rajesh Anandan
                                        Vice President, Corporate,
                                        Foundation & Sports Partnerships
                                        U. S. Fund for UNICEF
                                        (212) 992-2646
                                        ranandan@unicefusa.org

                                        Colleen Galbraith
                                        Manager, Corporate Partnerships
                                        U. S. Fund for UNICEF
                                        (212) 922-2635
                                        cgalbraith@unicefusa.org

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HIV/AIDS Innovation Fund Introduction

  • 1. A global partnership to accelerate the fight against HIV/AIDS
  • 2. CREATING A FAST LANE FOR CHANGE New interventions and technologies to change the face of HIV/AIDS “The future belongs to people who see possibilities before they become obvious.” — Ted Levitt, American Economist There are great ideas — simple, innovative, high-impact — emerging in the fight to prevent and treat HIV/AIDS. But a dearth of funds means some of the best never have the chance to come to life. The UNICEF HIV/AIDS Innovation Fund seeks to harness the greatest minds, most effective technologies, and best approaches to ensure even the hardest-to-reach children and families can lead healthy lives free of HIV. We invite you to join us in the next phase of the fight against HIV/AIDS.
  • 3. THE NEED FOR A NEW WAY FORWARD Working together toward an HIV-free generation 34 million people 2.5 million children — including — are living 400,000 children 900,000 with HIV/AIDS today. More than and adolescents become newly infected each year. Vast segments of affected populations — especially women and children — are not being reached by current approaches to prevention and treatment. At the same time, the funding gap between what is needed to respond to the global HIV/AIDS epidemic and what is available continues to grow, reaching $10 billion in 2010. There is an urgent need for a re-energized response to HIV/AIDS — to bring low-cost, high-impact interventions and technologies to scale. And we need your help.
  • 4. MOVING TOWARDS AN HIV FREE GENERATION 1.26 million children and young people are newly infected by HIV each year. By 2015 we aim to reduce this number by 50%. To do this UNICEF and partners will: Reduce new infant infection by 90% Reduce new youth infection by 30% From 370,000 to 37,000 From 890,000 to 623,000 Each figure represents 10,000 children newly infected each year.
  • 5. A FUND TO BRING INNOVATION TO SCALE The UNICEF HIV/AIDS Innovation Fund brings together top HIV experts with diverse business and philanthropic leaders to invest in high-impact, low-cost interventions and technologies that can change the face of the AIDS epidemic. How it works: UNICEF sources the most The Fund incubates UNICEF works with governments, innovative ideas these ideas, NGOs, academia, and multilateral — with the power to address providing financing partners to bring the most unmet needs and hard-to-reach successful projects to 3 and expertise through populations — from experts the pilot phase. scale, breaking bottlenecks, 1 and partners working in boosting capacity, and encourag- more than 150 countries. ing new commitments. 4 The Fund’s Advisory Funders and partners receive Committee recommends narrative and financial reports the highest- helping them monitor potential investments and continually projects align funding with the most effective 2 for seed funding. innovations. 5
  • 6. KEY ELEMENTS OF THE INNOVATION FUND Rapid, flexible resources building a pathway to scale • Pooled fund of $4-5 million/year. • Transparent criteria and process for selection of projects, including defined metrics for measuring success/impact. • Provision of rapid, flexible resources during the early stages of a project’s life cycle, building a pathway to scale up by governments and donors. • Advisory Committee comprised of HIV experts and lead funders working together to recommend the highest-potential projects for seed funding. • External/private sector expertise leveraged to strengthen projects as needed. • Five year initial phase from 2011 to 2015, with annual review of results and impact.
  • 7. INNOVATION FUND TARGET AREAS FOR INVESTMENT Investing for impact Solutions for “Last Mile” Delivery • Strengthen drug and local supply chains • Ensure drug delivery and uptake by hardest-to-reach populations • Facilitate improved disease reporting, test result delivery and treatment monitoring • Develop open-source mobile technology for integrated health services Innovation in the Youth Agenda • Reimagine youth-friendly HIV/AIDS prevention and treatment platforms • Empower youth through technology, social networks, and other new media • Enable peer-to-peer communication and support Strengthening Families and Communities • Build social and economic systems that incentivize well-being and facilitate access to health care for the hardest-to-reach • Design resources for community-based healthcare and education. Optimizing Management Systems • Maximize cost effectiveness of interventions and outcomes • Improve data use and management
  • 8. INNOVATION FUND PROJECT SELECTION CRITERIA Breaking bottlenecks, delivering results, positioning for scale • Focus on new interventions and technologies, or innovations to current approaches that contribute to reducing the impact of HIV/AIDS on women and children. • IIdentify specific bottlenecks to be addressed and show how the project can help change the HIV/AIDS landscape. • Be evidence-based and contribute on-the-ground results within 2–3 years. • Demonstrate how “proof-of-concept” could lead to scale-up and funding by governments and donors. • lBuild on partnerships on the ground, link with national oversight. • Use existing global and national data and indicators to measure projects’ success. • lBe fundable with approximately $500K per project.
  • 9. INNOVATION: Results160 MOBILE HEALTH Example RapidSMS improves access to HIV test results and services for women and infants Bottleneck Transportation barriers and logistical delays lead to slow reporting If positive, child starts treatment of HIV test results, delaying Early Infant Diagnosis and inhibiting 13 If negative, child retested in 6 mos. treatment for mothers and infants. All pregnant mothers tested Mother retrieves DBS results from clinic, 1 0 & results are logged in child’s Under 5 Card 12 Solution Baby born to HIV+ mother 1 Mother is SMS RapidSMS mobile phone technology increases the number of 11 contacted System infants accurately tested for HIV and drastically reduces parents’ Results processed and sent to clinic via SMS 9 wait time for results. Results received by clinic worker & logged 10 LAB Lab receives Result CLINIC HUB CLINIC 2 8 samples 2 2 Low cost text messaging leads to 50% improvement in the DBS Sample DBS Sample 2 DBS Sample DBS Sample DBS Sample Hub Clinic receives & logs samples delivery of HIV results for infants and helps ensure treatment DBS sample taken at 6 rural clinic availability and adherence. 2 DBS Sample DBS Sample DBS Sample DBS Sample 1 DBS Sample 7 Hub aggregates samples Benefits 3 Samples packed & logged 1 5 Samples transported and sends to Lab 7 • Speed — Wait time for test results cut from months to days. Dried Blood Spot (DBS) to district Hub Clinic • Cost — No SMS cost for clinic staff. Sample DBS Sample DBS Sample DBS Sample 4 SMS “SENT #” samples • Scale — Potential for national scale at low cost. • Reporting — Web portal provides national view of HIV rates and treatment.
  • 10. OPPORTUNITIES TO HELP DRIVE THE HIV/AIDS INNOVATION FUND UNICEF and Business and Philanthropic leaders changing the face of HIV/AIDS UNICEF as a Partner for Innovation UNICEF has offices in more than 150 countries worldwide, and a long history of identifying and scaling innovative solutions to development challenges. We are looking for partners who share our belief that the next step in the fight against HIV/AIDS calls for new col- laboration models and a willingness to embrace innovation. Become a Seed Funder Make a substantial, multi-year contribution to help seed the Fund and you’ll join the Fund’s Advisory Committee — a multi-disciplinary group of corporate and philanthropic leaders, and top HIV experts. Leverage Your Network If you know investors for whom the Innovation Fund would be of interest, please put them in touch with the U.S. Fund for UNICEF.
  • 11. CONTACT US For more information, please contact: Rajesh Anandan Vice President, Corporate, Foundation & Sports Partnerships U. S. Fund for UNICEF (212) 992-2646 ranandan@unicefusa.org Colleen Galbraith Manager, Corporate Partnerships U. S. Fund for UNICEF (212) 922-2635 cgalbraith@unicefusa.org